Researchers have discovered three patterns of tumor evolution: single cell ¨survives, multiple cells ¨survive in one place and wrestle with each other, multiple cells ¨survive in different places.
Researchers have discovered three patterns of tumor evolution: single cell ¨survives, multiple cells ¨survive in one place and wrestle with each other, multiple cells ¨survive in different places. An international team under the leadership of Würzburg and Heidelberg has deciphered central evolutionary mechanisms in multiple myeloma. According to the study, even a single surviving tumor cell can lead to relapse. Which tumor cells survive chemotherapy? Where does relapse come from? Unfortunately, all patients suffering from multiple myeloma have to fear a relapse. There is still no cure for this cancer of the bone marrow, which affects six to eight out of every 100,000 people every year. However, with a better understanding of the evolution of these degenerate bone marrow cells, diagnosis and treatment could be optimized. Leo Rasche from Würzburg University Hospital and Niels Weinhold from Heidelberg University Hospital and their research groups have now made a valuable contribution to this in their latest publication in the journal Nature Communications.
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