Molecular Signatures can Predict the Efficacy of Malaria Vaccines

New study finds that molecular signatures can predict the efficacy of malaria va
New study finds that molecular signatures can predict the efficacy of malaria vaccines. (Photo: Danielle Powell / Swiss TPH).
New study finds that molecular signatures can predict the efficacy of malaria vaccines. (Photo: Danielle Powell / Swiss TPH). A new study reveals that it is possible to identify those individuals that will be protected by the malaria vaccine before its administration. The researchers also found that boosting the immune system before vaccination could potentially improve vaccine efficacy. The study was published yesterday in Science Translational Medicine by ISGlobal in partnership with the Swiss Tropical and Public Health Institute and other partners. Malaria remains a major public health problem, causing almost 200 million cases and over 400,000 deaths in 2018. The main obstacles for the development of an effective vaccine against such a complex parasite are the lack of immune markers of protection and the poor understanding of the mechanisms underlying such protection.
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