The cells were taken from the rainbow trout. (Photo: Andreas Hartl)
The cells were taken from the rainbow trout. (Photo: Andreas Hartl) - The "gene scissors" CRISPR/Cas9 can be used to precisely modify genes in order to study their function in an organism. A researcher at Eawag has now succeeded for the first time in establishing the gene scissors for a fish cell line of rainbow trout. This means that, as of now, genetically modified cell lines can be produced. These allow alternatives to ecotoxicological tests on living animals. "When I came to Eawag in 2019, I didn't do anything much at first other than to try to get RNA into fish cells," says Marina Zoppo, a postdoctoral researcher at the aquatic research institute Eawag. RNA is a molecule in biological cells that occurs in different forms.
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