Dr Tanya Soboleva in the lab. Photo: supplied
Dr Tanya Soboleva in the lab. Photo: supplied - Researchers at The Australian National University (ANU) have discovered how a DNA-binding protein sustains Hodgkin lymphoma. The world-first discovery has the potential to help treat the rare cancer with the development of therapeutics that target cells once they become cancerous. The findings are published in EMBO Reports . Approximately 800 Australians are diagnosed with Hodgkin lymphoma per year. The disease causes cancer in white blood cells, called lymphocytes, in men and women of any age, but young people in particular. The research team discovered the histone protein, H2A.B that is normally active only in the testes and the brain, becomes abnormally activated in lymphocytes, stimulating conditions that sustain Hodgkin lymphoma.
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