The Molecular Oncology research group at USI has identified, through the use of bioinformatics and artificial intelligence, a new way to selectively identify and kill a specific type of cells involved in metastasis dissemination. The problem Metastasis, the spreading of tumor cells from a primary site to their progressive outgrowth at a distant organ, is ultimately what kills almost 90% patients with cancer. Yet, we are only at the cusp of our understanding of the biology of metastasis. So far little is known about why and how cancer cells migrate and invade away from the primary tumor. Nowadays, the clinic lacks an effective therapy to prevent this detrimental stage. Martina Troiani and Manuel Colucci two Ph.D. students in the team of Prof. Andrea Alimonti , MD at the Institute of Oncology Research (IOR, affiliated to USI and member of Bios+) have therefore identified a novel therapy to impairs metastasis formation.
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