Computational models reveal effects of pregnancy on kidneys

Returning to in-person experiences in February: for more information. The computational models will help medical practitioners better understand the physiology of the kidneys during pregnancy Researchers are using computer simulations to better understand the impacts pregnancy can have on kidneys. The new research will help medical practitioners better understand the physiology of the kidneys during pregnancy and develop appropriate patient care and treatments to improve health outcomes. The researchers are interested in how the kidneys change during a typical pregnancy and how increased strain on the kidneys can lead to gestational diseases. The kidneys can also be affected by preeclampsia - unusually high blood pressure during pregnancy that may lead to organ damage. "One thing that happens during pregnancy is that plasma volume expands to supply a developing fetus and placenta," said Melissa Stadt, a master's researcher in applied mathematics at the University of Waterloo. "There's also retention of extra sodium and potassium, which are essential electrolytes during pregnancy.