The photo shows a fluorescent microscopic image of mitochondrial networks (green) and cell nuclei (blue) from human cell lines. Photo: Pablo Sánchez-Martín
The photo shows a fluorescent microscopic image of mitochondrial networks ( green ) and cell nuclei ( blue ) from human cell lines. Photo: Pablo Sánchez-Martín - New findings make it possible to explore in detail the links between defects in mitochondrial proteins and diseases of the cardiovascular and nervous systems Mitochondria are key components of our cells. Cell respiration and control of many metabolic and signalling processes take place within them. In order for the biochemical reactions to take place flawlessly, complex interactions between specialized protein molecules are required. Yet up to now, it wasn't known how many of the proteins in cells are also actual components of the mitochondria because the technology for such precise allocation was unavailable. A team working with Bettina Warscheid , Nils Wiedemann , Nikolaus Pfanner and Claudine Kraft of the Excellence Cluster CIBSS Centre for Integrative Biological Signalling Studies at the University of Freiburg, and Dr. Sven Dennerlein of the University of Göttingen, have used new methods to examine successfully and precisely the composition human mitochondria. Their results are appearing in a study in the specialist journal, "Cell Metabolism".
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