How immunity contributes to ageing and neurodegeneration

An activated microglia cell in the brain of cGAS/STING activated mice. Credit: G
An activated microglia cell in the brain of cGAS/STING activated mice. Credit: Gulen et al. Nature 02 August 2023. DOI: 10.1038/s41586’023 -06373-1 (0)
An activated microglia cell in the brain of cGAS/STING activated mice. Credit: Gulen et al. Nature 02 August 2023. DOI: 10.1038/s41586'023 -06373-1 (0) Researchers at EPFL have found that a specific immune signaling pathway drives ageing-related inflammation and neurodegeneration. The work can help us understand the mechanisms behind ageing-associated impairment and disease. As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases. One common factor in the ageing process is low-grade inflammation, which contributes to age-related decline and impairment.
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