Our idea was to label sugar molecules with a chromophore, a chemical that gives a molecule its colour,’ explained Cecioni. ’The chromophore is actually fluorogenic, which means that it can become fluorescent if the binding of sugar with the lectin is efficiently captured. Credit: Cecioni Lab
Our idea was to label sugar molecules with a chromophore, a chemical that gives a molecule its colour,' explained Cecioni. 'The chromophore is actually fluorogenic, which means that it can become fluorescent if the binding of sugar with the lectin is efficiently captured. Credit: Cecioni Lab UdeM chemists have developed a new tool for detecting interactions between sugars and lectins, a discovery that could help in the fight against diseases like cancer. Scientists at Université de Montréal's Department of Chemistry have developed a new fluorogenic probe that can be used to detect and study interactions between two families of biomolecules essential to life: sugars and proteins. The findings by professor Samy Cecioni and his students, which open the door to a wide range of applications, were published in mid-October in the prestigious European journal Angewandte Chemie . Found in all living cells. Sugar is omnipresent in our lives, present in almost all the foods we eat.
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