Cynthia Sharma, head of the Chair of Molecular Infection Biology II and spokesperson of the Research Center for Infectious Diseases (ZINF) at the Julius-Maximilians-University Würzburg. (Image: Petra Thomas (IMIB))
Cynthia Sharma, head of the Chair of Molecular Infection Biology II and spokesperson of the Research Center for Infectious Diseases (ZINF) at the Julius-Maximilians-University Würzburg. (Image: Petra Thomas (IMIB)) 03/17/2022 - Cynthia Sharma studies how bacteria adapt to changing environments, focusing on RNA-binding proteins, about which very little is known so far. For this, she has now received an ERC Consolidator Grant endowed with two million euros. When bacteria such as the foodborne pathogens Campylobacter jejuni or Salmonella infect humans, they usually encounter a hostile environment. However, thanks to various mechanisms, they can adjust to these conditions and have developed sophisticated survival and adaptation strategies. Within the framework of a new research project, Cynthia Sharma focuses on a specific area of such cellular control that bacteria use to regulate their genes in response to environmental changes. Sharma and her team will explore a class of proteins that can bind RNA molecules and thereby exert major influence on gene expression and cellular processes in bacteria.
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