Combating cancer’s double whammy

PA 311/10 A major study is under way at The University of Nottingham which could lead to better prevention of a serious and sometimes fatal complication in cancer patients. Venous thromboembolism (VTE or 'blood clotting') is one of the most common causes of death in the UK and 20 per cent of these deaths are in people with cancer who are more at risk. VTE occurs when a blood clot forms in a deep vein. It can be fatal if the clot breaks away and lodges in the lung (pulmonary embolism). The aim of this analysis of primary care data is to establish a clearer picture of the increased risk of venous thromboembolism in different cancers, and to help create bespoke guidelines for doctors in how to prevent the condition arising after a cancer diagnosis. The three year study is being carried out in the University's Division of Epidemiology and Public Health. Researchers believe that some 3,000 deaths a year in cancer patients from VTE could potentially be prevented using cheap and safe preventative treatments known as thromboprophylaxis when targeted at the most appropriate times; the most widely used are warfarin and heparin.