Shiranee Sriskandan
Shiranee Sriskandan - Imperial and US scientists are spearheading a multi-institution network to research bacterial cause of sepsis and heart damage in children. Each year, around half a million people, including many children and young people, die around the world because of serious group A streptococcal (Strep A) bacterial infections. While most cases are relatively mild - affecting only the skin or throat - some infections can lead to deadly sepsis or autoimmune damage to the heart. There is currently no available vaccine for Strep A. The newly launched iSpy Network ( i mmunity to S treptococcus ogenes) brings together 28 investigators from 11 countries worldwide, including experts in immunology, infectious disease, epidemiology, vaccinology and experimental medicine. The iSpy Network is led by Imperial College London alongside the University of California San Diego (UC San Diego), supported by funding from the Leducq Foundation. Victor Nizet - Imperial's Professor Shiranee Sriskandan from the Department of Infectious Disease heads one of two iSpy sub-networks, called iSpy-LIFE. She comments: "In recent years we've seen a concerning upsurge of Strep A in the UK, with a significant number of deaths among children.
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