Image of patient-derived endocervical columnar (red) ectocervical stratified squamous organoids (Green) of female reproductive tract, and diagram depicting their genetic manipulation and infections. (Image: AG Chumduri)
Image of patient-derived endocervical columnar ( red ) ectocervical stratified squamous organoids ( Green ) of female reproductive tract, and diagram depicting their genetic manipulation and infections. (Image: AG Chumduri) 05/13/2022 - Life-like organ replicas - so-called 3D organoids - are a good way to research disease processes. A team from the University of Würzburg has now presented a kind of blueprint for such a model of the cervix. A few stem cells, various growth factors, four to six weeks of time - and of course a great deal of expertise are needed to create a scaled-down but nevertheless lifelike and functional replica of a cervix in the laboratory. A new publication that has now appeared shows how the process works in detail. Dr. Cindrilla Chumduri, head of the research group at the Department of Microbiology at the Julius Maximilians University of Würzburg (JMU), is responsible for this. The infection and cancer biologist has been researching the physiological processes in the cervical tissue for a long time.
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