(© Image: Depositphotos) The development of head and neck cancer is increasingly linked to HPV infection, which is a sexually transmitted disease. Oropharyngeal cancer is a type of head and neck cancer that is associated with preconceptions regarding the high-risk sexual behaviour of the affected individuals. Circumventing some potential sources of bias related to case-control studies, researchers at the University of Leipzig Medical Center conducted a nested case-control study which utilised consecutive accrued OPSCC cases and matched healthy controls from the LIFE population-based cohort study to answer the question of whether high-risk sexual behaviour - oral sex, in particular - is a relevant aetiologic factor in the development of HPV-related OPSCC. The study was recently published in the journal -Cancers-. Human papillomavirus (HPV) is a ubiquitous virus, and most people are infected at some point in their lives. HPV can infect epithelial cells of the skin and mucosa at various sites. There are more than 100 known HPV subtypes, most of which cause only benign lesions such as warts and condyloma.
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