New research led by Mariya Goncheva, has shown that a protein found in all strains of Staph A. enhanced SARS-CoV-2 replication by 10- to 15-fold. (Schulich Medicine & Dentistry Communications)
New research led by Mariya Goncheva, has shown that a protein found in all strains of Staph A. enhanced SARS-CoV-2 replication by 10- to 15-fold. (Schulich Medicine & Dentistry Communications) Western study finds co-infection with 'superbug' bacteria increases SARS-CoV-2 replication The study identifies a common protein from the Staphylococcus aureus bacteria boosts SARS-CoV-2 replication up to 15 times By Prabhjot Sohal , March 20, 2023 By Prabhjot Sohal , March 20, 2023 Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection - with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2. Researchers at Western have found if you add a 'superbug' - methicillin-resistant Staphylococcus aureus (MRSA) - into the mix, the COVID-19 outcome could be even more deadly. The mystery of how and why these two pathogens, when combined, contribute to the severity of the disease remains unsolved. However, a team of Western researchers has made significant progress toward solving this "whodunit". New research by Mariya Goncheva , Richard M. Gibson , Ainslie C. Shouldice, Jimmy D. Dikeakos David E. Heinrichs , has revealed that IsdA, a protein found in all strains of Staph A., enhanced SARS-CoV-2 replication by 10- to 15-fold. The findings of this study are significant and could help inform the development of new therapeutic approaches for COVID-19 patients with bacterial co-infections.
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