New method for localizing modifications in mRNA

To prepare the mRNA samples, the researchers add magnetic beads to the vessels.
To prepare the mRNA samples, the researchers add magnetic beads to the vessels. The modified mRNAs bind specifically to these "beads’. With the help of a magnet (white block) behind the vessels, the modified mRNAs are enriched. The series of images (one to four) shows how the "beads’ with the mRNA accumulate on the back of the vessel within about one minute. Uni MS - Nadine Kück
Andrea Rentmeister's team detects methylated sites with click chemistry. To prepare the mRNA samples, the researchers add magnetic beads to the vessels. The modified mRNAs bind specifically to these "beads'. With the help of a magnet (white block) behind the vessels, the modified mRNAs are enriched. The series of images (one to four) shows how the "beads' with the mRNA accumulate on the back of the vessel within about one minute. Uni MS - Nadine Kück The genetic information of an organism is stored in the form of DNA (deoxyribonucleic acid) in every cell. In order to be able to produce proteins with this blueprint, the DNA is first transcribed into so-called mRNA (messenger ribonucleic acid).
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