Diabetes and depression predict dementia risk in people with slowing minds

People with mild cognitive impairment are at higher risk of developing dementia if they have diabetes or psychiatric symptoms such as depression, finds a new review led by UCL researchers. Mild cognitive impairment (MCI) is a state between normal ageing and dementia, where someone's mind is functioning less well than would be expected for their age. It affects 19% of people aged 65 and over, and around 46% of people with MCI develop dementia within 3 years compared with 3% of the general population. The latest review paper, published in the American Journal of Psychiatry , analysed data from 62 separate studies, following a total of 15,950 people diagnosed with MCI. The study found that among people with MCI, those with diabetes were 65% more likely to progress to dementia and those with psychiatric symptoms were more than twice as likely to develop the condition. "There are strong links between mental and physical health, so keeping your body healthy can also help to keep your brain working properly," explains lead author Dr Claudia Cooper (UCL Psychiatry). "Lifestyle changes to improve diet and mood might help people with MCI to avoid dementia, and bring many other health benefits.