Electron microscopy reconstruction of the various bacterial niches.
Electron microscopy reconstruction of the various bacterial niches. Credit: Sharma et al. EPFL - Scientists at EPFL have developed two complementary bladder models to study urinary tract infections (UTIs) caused by E. coli: bladder organoids and a bladder-on-a-chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune system and resist antibiotics. The studies they provide researchers and clinicians with a powerful new for studying the pathogenesis and treatment of UTIs. Solitary isolated bacteria in the bladder wall are protected from clearance by neutrophils. Credit: Sharma et al. Urinary tract infections (UTIs) are among the most common bacterial infections.
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