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Half a million people worldwide are diagnosed with esophageal cancer every year. It is one of the deadliest forms of cancer. A study with significant involvement from Leipzig University Medicine shows how the chances of recovery for patients can be improved. The results were published in the renowned New England Journal of Medicine.

Researchers have discovered and analyzed a rare but serious side effect of an innovative form of blood cancer therapy. The results of the study have been published by scientists from Leipzig University Medicine, the Fraunhofer Institute for Cell Therapy and Immunology and Cologne University Hospital in the high-ranking journal Nature Medicine.

A new study shows how the brain reorganises itself in the first few months after a stroke to improve the ability to speak again. The findings will help researchers understand how functional networks work in the brain. They also have the potential to be used in the future for personalised treatment of stroke patients.

A recent study shows how the brain reorganizes itself in the first few months after a stroke in order to improve language ability. The findings help to better understand the functioning of functional networks in the brain. They also have the potential to be used in personalized therapy after a stroke in the future.

An interdisciplinary research team from Leipzig University and the Saxon AI center ScaDS.AI have developed a new approach that combines methods of artificial intelligence (AI) and biophysical modeling. This new approach can be used to develop new active substances such as antibodies and vaccines, for example for pandemic prevention.

In a recent study, scientists at Leipzig University have for the first time demonstrated play-like behaviour in flies. They found that fruit flies (Drosophila melanogaster) voluntarily and repeatedly visited a carousel. "Until now, play-like behaviour has mainly been described in vertebrates," says Professor Wolf Huetteroth, who led the study at the Institute of Biology at Leipzig University and recently moved to Northumbria University in Newcastle, England, as an associate professor.

News from Since the Industrial Revolution, global changes have driven declines in biodiversity. Understanding, protecting, and constructing healthy ecosystems is crucial to addressing these changes. A new meta-analysis by an international team including Professor Nico Eisenhauer (iDiv, Leipzig University) revealed that the soil engineering effects of the three major invertebrate groups - termites, earthworms, and ants - can enhance soil nutrient contents, soil respiration rates, microbial biomass, and plant biomass at a global scale.

Since the industrial revolution, global changes have led to a decline in biodiversity. To counter these changes, it is crucial to understand what constitutes healthy ecosystems - and how to protect and build them.

In a recent study, scientists at Leipzig University have demonstrated the potential play behavior of flies for the first time. They found that fruit flies (Drosophila melanogaster) voluntarily and repeatedly visit a carousel. "Until now, play behavior has mainly been described in vertebrates," says Wolf Hütteroth, who led the study at Leipzig University's Institute of Biology and recently moved from Leipzig to Northumbria University in Newcastle, England, as an Associate Professor.

In addition to the traditional press releases, Leipzig University provides information on current topics in the form of short news items. This time about two high-ranking research publications from the Faculty of Medicine. More strength in the muscles: Researchers discover new mechanism for male sex hormone Researchers at Leipzig University Medicine and Shandong University in China have discovered a new mechanism by which a male sex hormone, which is essential for muscle and bone function, can exert its effect.

Body weight and body mass index alone say too little about whether someone will develop metabolic disorders. A new atlas of cells in adipose tissue could now help to decipher why some overweight people remain healthy and others do not. The results have been published in the journal Cell Metabolism with the lead participation of Leipzig University Medicine.

Researchers at Leipzig University Medicine and Shandong University in China have discovered a new mechanism by which a male sex hormone, which is essential for muscle and bone function, can exert its effect. Based on these findings, new drugs with fewer side effects could be developed that are used, for example, to strengthen the muscles of immobile patients.

Spinal muscular atrophy affects all the body's muscles. For a long time, it was considered a disease caused solely by the loss of nerve cells in the spinal cord. Now, a research team at Leipzig University's Carl Ludwig Institute of Physiology has been able to show that the cerebellum - which is important for motor coordination but also influences social and cognitive processes - also plays a role in the development of spinal muscular atrophy.

Adhesion GPCRs are a group of cell surface sensors that are associated with many bodily functions and diseases. However, they have not yet been sufficiently investigated in order to use them for therapies. The Collaborative Research Center 1423 at Leipzig University aims to change this. Scientists from the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain that is common to all adhesion GPCRs.

News from A new study that provides unprecedented insights into the chemical bonding of antimony could have a profound impact on materials research. The collaboration between scientists from Leipzig University, RWTH Aachen University and the DESY synchrotron in Hamburg combined experimental measurements with theoretical calculations.

A recent study provides new insights into chemical bonding in the chemical element antimony and could therefore have a lasting impact on materials research. The collaboration between scientists from Leipzig University, RWTH Aachen University and the DESY synchrotron in Hamburg combined experimental measurements with theoretical calculations.

Researchers at Leipzig University have developed a new process for reversing the polarity of chemical compounds, also known as umpolung, for the precise synthesis of pharmaceuticals. This innovative method, developed by a team of scientists led by Professor Christoph Schneider at the Institute of Organic Chemistry, provides a solution-oriented approach to a long-standing challenge in organic and medicinal chemistry," says Till Friedmann, lead author of It has just been published in the prestigious Journal of the American Chemical Society.

News from Understanding biological relationships is often critical when studying animal populations. Researchers from the Max Planck Institute for Evolutionary Anthropology, Leipzig University, the German Centre for Integrative Biodiversity Research (iDiv) and the Freie Universität Berlin have now developed a transformative approach that identifies stretches of DNA that two individuals inherited from a common ancestor.

An estimated four million people in Germany suffer from heart failure, and around half of these patients have heart failure with preserved pumping function. What influence does endurance and strength training have on the progression of this often life-threatening disease? The world's most comprehensive study to date, which was led by scientists from the German Heart Center at Charité Berlin, University Medicine Leipzig, University Medicine Rostock and TUM University Hospital Munich and published in the journal Nature Medicine, provides important insights into this question.

A new study in the journal Nature shows that the oceans were less cold in the early 20th century (1900-1930) than previously thought. During this period the ocean appears too cold due to the way some measurements were taken. This makes global ocean surface temperature measurements during this period inconsistent with both land air temperatures and palaeoclimatic data and the differences between land and ocean are larger than shown in climate models.