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A new study led by researchers from Trinity and the Moffitt Cancer Center shows how radiation therapy can be used to expose-and then eliminate-therapy-resistant cancer cells using natural killer cell immunotherapy. Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in complete remission.

In infectious disease research, disrupting bacterial communication is widely considered beneficial. A study by UNIGE and NTU Singapore shows this is not always true. Is blocking bacterial communication always beneficial? A team from the University of Geneva and Nanyang Technological University, Singapore (NTU Singapore) challenges a widely held assumption in infectious disease research.

The research, which focused on the cerebellum, identifies the link between aging-related brain cell changes and declines in motor skill A new McGill University study has found a direct link between age-related declines in neuron activity in the cerebellum and worsening motor skills, including gait, balance and agility.

Scientists have found new clues about how the brains of people with Down syndrome develop differently from a very early age, in a study led by researchers at UCL and Queen Mary University of London. Brain cells with an extra copy of a chromosome (trisomy 21) - the genetic cause of Down syndrome - have difficulty forming strong, well-coordinated connections with each other, according to the new  Nature Communications study.

In sea urchin and salmon sperm, the pH value regulates whether they remain immotile or swim A study by the Max Planck Institute for Multidisciplinary Sciences and the University of Bonn has shown that pH value is crucial for sperm motility in sea urchins and salmon. An increase in pH activates the enzyme adenylyl cyclase (sAC), which produces the messenger substance cAMP, thereby regulating sperm motility.

Myasthenia Gravis (MG) is a rare autoimmune disease in which the immune system attacks the connection between nerves and muscles. This attack causes muscle weakness that can affect vision, movement, speech, swallowing, and breathing. While many patients respond to treatment, others develop a severe, treatment-resistant form of the condition known as refractory MG.

An international team of scientists led by the Institute of Cosmos Sciences at the University of Barcelona (ICCUB) and the Institute of Space Studies of Catalonia (IEEC) has presented REGALADE, an unprecedented catalogue covering the entire sky and bringing together nearly eighty million galaxies. The work, published in the journal Astronomy & Astrophysics , marks a turning point for astronomy and opens up a new scenario that allows researchers to explore cosmic events with a degree of precision never before achieved.

An international research team, with significant involvement from the Medical University of Vienna, has developed a new AI-based analysis method that can accurately classify brain tumours using genetic material from cerebrospinal fluid (CSF) and monitor the progression of the disease. In future, the method could enable earlier diagnosis before surgery, reduce invasive procedures and improve the monitoring of treatment success.

New Trinity study is first of its kind in Ireland to specifically focus on women to address the disproportionately poor physical health of this population when compared to the general population. A study published by Trinity College researchers from the School of Medicine in the journal BMJ Open , explored the effect of an exercise programme in a Dublin day centre for women who are dealing with challenging issues.

A researcher's keen eye and spirit of curiosity led to the discovery of a new method for cell engineering - a finding that opens doors to more sustainable sources for everything from fuel to vitamin supplements. Western graduate Emma Walker, PhD'25, uncovered a more effective way to deliver DNA into diatoms, single-celled algae found near the surface of oceans, lakes and rivers.

Researchers have identified a 'tipping point' about 2.7 million years ago when global climate conditions switched from being relatively warm and stable to cold and chaotic, as continental ice sheets expanded in the northern hemisphere. Following this transition, Earth's climate began swinging back and forth between warm interglacial periods and frigid ice ages, linked to slow, cyclic changes in Earth's orbit.

Researchers believe this study further highlights that a key immune system switch warrants full investigation in MS and may be a promising potential target for future MS therapies. Trinity College Dublin researchers have published a new study on MS that has uncovered evidence that a key immune system switch, known as the NLRP3 inflammasome, may play a significant role in the inflammatory processes associated with the pathogenesis of MS.

Flexible electronics are often sold on a simple promise: bendable screens, lightweight solar cells or wearable devices that can bend and flex without breaking. But what does that 'flexibility' actually look like at the molecular scale, and how does it affect performance? Researchers led by the University of Cambridge say they have taken a first step towards answering this question.

Why do some melodies feel instantly right, balanced, memorable and satisfying, even if you have never heard them before? New research from the University of Waterloo suggests that more than creativity is at play. Behind many great melodies, researchers found something surprisingly powerful: symmetry.

A study published in Nature Communications shows that water resulting from ice melting has increased six-fold in recent decades. A study led by the University of Barcelona and published in the journal Nature Communications shows that climate change has profoundly altered extreme episodes of melting of the Greenland ice sheet: it has made them more frequent, more extensive and more intense.

Researchers from the University of Southern Denmark have identified a new virus in a common gut bacterium. The virus is found significantly more often in patients with colorectal cancer. Colorectal cancer is one of the most common types of cancer in the Western world and a leading cause of cancer-related deaths.

Chemists synthesise high-tensile ring molecules through photocatalysis / Components for drug development When developing new drugs, one thing is particularly important: finding and producing the right molecules that can be used as active ingredients. The key elements of some drugs, such as penicillin, are small, trior quadripartite ring molecules.

A research team at Universidad Carlos III de Madrid (UC3M) has developed technology using advanced machine learning techniques that detects signs of gender violence from paralinguistic characteristics of the voice such as tone, rhythm, and intensity. This innovative method helps to recognize situations of psychological stress or trauma while preserving the privacy of the speakers, which could have major implications for telephone helplines and telemedicine services.

Researchers at the Inselspital, Bern University Hospital, and the University of Bern have, for the first time, directly measured how the human brain exchanges probing signals when asleep and when awake. Using electrodes temporarily implanted in the brain for clinical reasons, they were able to track the flow of signals between deep brain regions and the cerebral cortex with millisecond accuracy over a period of 24 hours.

Study finds that those who see themselves as having darker complexions compared to other Black Americans show markers associated with poorer health outcomes A study of Black Americans is among the first to show how the internalization of negative messages about dark skin tones could be linked to harms to health.