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Experts are increasingly turning to machine learning to predict antibiotic resistance. The results should be treated with caution, as a new study by HIRI shows. Antibiotic-resistant infections are a growing threat worldwide. Instead of culturing bacteria in the traditional way and testing their response to antibiotics, laboratories are increasingly analyzing bacterial genetic material to spot resistance early.

Research team discovers unique quantum state at the interface of organic and 2D semiconductors Faster, more efficient, and more versatile - these are the expectations for the technology that will produce our energy and handle information in the future. But how can these expectations be met? A major breakthrough in physics has now been made by an international team of researchers from the Universities of Göttingen, Marburg, the Berlin Humboldt in Germany, and Graz in Austria.

Long COVID remains a complex and often invisible condition. Patients experience symptoms such as extreme fatigue, exercise intolerance, shortness of breath, cognitive impairment, and a pervasive sense of exhaustion for months or even years after a SARS-CoV-2 infection. Because these symptoms are not always objectively detectable through conventional medical tests, patients are frequently told that "everything looks normal", even though their daily lives remain severely restricted.

Researchers have developed the first scientifically validated 'personality test' framework for popular AI chatbots, and have shown that chatbots not only mimic human personality traits, but their 'personality' can be reliably tested and precisely shaped - raising implications for AI safety and ethics.

Danish-Australian study shows that the effect of triple combination therapy depends on genetic changes in the tumour's signalling pathways. Hormone receptor-positive (ER+) breast cancer is the most common type of breast cancer worldwide. Patients with this typer of cancer in advanced stages are treated with a combination of hormone therapy and CDK4/6 inhibitors, which often inhibits tumour growth.

The bacterial pathogen Xanthomonas citri , which causes canker disease in citrus trees, activates selected parts of the fruit ripening program inside infected leaves. Normally, this program makes citrus fruits soften and sweeten as sugars are released. But the bacterium hijacks this fruit-specific machinery in infected leaf tissue, causing the host to unlock sugars that otherwise would not be accessible to Xanthomonas as a source of nutrients.

Astronomers have repeatedly observed events near a distant star that mirror processes from the early solar system-s planet-forming era Powerful collisions observed in space: Hubble images show the formation of two enormous dust clouds caused by collisions between kilometre-sized celestial bodies in the young planetary system around the star Fomalhaut.

Antibiotic resistance is a  growing global health crisis that makes common infections harder to treat and puts many medical procedures at risk. Now, Carnegie Mellon researchers have uncovered a vulnerability in bacteria that could pave the way for an entirely new class of treatments. The discovery, published today in Nature Communications , doesn't kill the bacteria - a tactic that often leaves behind resistant survivors - but targets a key mechanism that controls bacterial behavior.

Researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a full-blown immunotherapy strategy. Cancer immunotherapy is a strategy that turns the patient's own immune cells into a "search-and-destroy" force that attacks the tumor's cells.

A team of researchers from Universidad Carlos III de Madrid (UC3M) and Universidad Politécnica de Madrid (UPM) has developed an innovative algorithm for Wi-Fi networks called "Ponte" that can provide

When studying how fossil hominids moved, researchers usually analyse the morphology of bones - which is crucial for understanding the evolution of bipedalism - focusing mainly on muscle insertion sites. However, the potential information of studying other types of soft tissue, such as joint ligaments, is often overlooked.

A research team at the Leibniz Institute for Natural Product Research and Infection Biology (Leibniz-HKI) and Friedrich Schiller University Jena describes a new enzyme in the journal »Angewandte Chemie International Edition« that renders the highly toxic molecule malleicyprol harmless. Malleicyprol is considered an important virulence factor of Burkholderia bacteria, which cause, among other things, the dangerous tropical disease melioidosis.

Mouse geneticist Antoine Peters and his team investigate how information beyond the DNA sequence - shaped by chemical marks on the DNA molecule - controls the earliest steps of life. By revealing how errors in these mechanisms can silence essential genes and prevent embryos from implanting, this work may shed light on the molecular causes of infertility.

In cooperation with MedUni Vienna, researchers at TU Vienna have investigated how 3D bioprinting can be used specifically to produce complex skin models as part of a recent review. The study shows that, by using suitable biomaterials and precise printing technologies, it is possible to create multi-layered skin structures into which immune cells can also be integrated - a decisive step in advancing research into chronic inflammatory skin diseases such as psoriasis.

Among sharks and rays, species within the first four million years of existence are significantly more likely to go extinct than older species, according to a study led by researchers from the University of Zurich based on fossils from the last 145 million years. This shows that in addition to environmental stressors, the evolutionary age of species also plays a crucial role in their survival.

Use of nicotine pouches has risen substantially in Great Britain over the last five years, particularly among young men, with one in 13 (7.5%) men aged 16 to 24 now using them, according to a new study led by researchers at UCL. The study, published in the journal Lancet Public Health and funded by Cancer Research UK, found that use of pouches overall had increased from 0.1 to 1% of all'adults, equivalent to about 522,000 people.

Do animals think and feel? How this question is answered has a direct bearing on how empathetically and considerately people treat animals.

Research team led by Göttingen University compares forest soils in different ecosystems in Chile Wildfires may disappear from the landscape within weeks, but their hidden effects on the soil can persist for decades. An international research team led by the University of Göttingen, together with partners in Tübingen, Berlin and Chile, has shown how wildfires in humid temperate rainforests and mediterranean woodlands of central Chile lead to very different pathways of soil recovery and ecosystem resilience.

Preclinical results show movement relies on a steady supply of dopamine, helping explain why current treatments work and how they could be improved  A McGill-led study is challenging a popular theory about how dopamine drives movement, a discovery that could shift how scientists think about Parkinson's disease treatments.

Three-dimensional multicellular human liver model: For the first time, a 3D human organoid model, developed with liver tissue from patients, consists of three liver cell types, derived from adult hepatocytes, cholangiocytes, and liver mesenchymal cells. Retaining structure and function: The novel complex organoid models, or assembloids, reconstruct essential structural and functional features of the human periportal liver region and have patient-specific traits.