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A cellular resistance mechanism at the origin of relapses of triple-negative breast cancer has recently been discovered by scientists from CNRS, Institut Curie and Université Paris Cité. Their findings have been published in Cancer Research, a journal of the American Association for Cancer Research, on 6 November 2025.

Even in sunny forest gaps, browsing by roe deer prevents the natural regeneration of many tree species. Researchers at the University of Würzburg show just how strongly these ungulates shape forest development. In the current issue of the Journal of Applied Ecology, researchers from Julius-Maximilians-Universität Würzburg (JMU) report that roe deer restrict the natural regeneration of deciduous forests far more than previously assumed.

People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by UCL researchers. The study, published in the European Heart Journal and funded by the British Heart Foundation, found middle-aged people with higher levels of a protein called cardiac troponin I in their blood were more likely to go on to develop dementia in later life.

Scientists have developed a simple, low-cost method to drive key chemical reactions, which could make large-scale drug manufacturing, faster, more accessible and affordable. The new study, published in the journal Nature Synthesis today by The University of Manchester, describes how complex light or electricity-mediated methods currently used across modern chemistry could be replaced by those driven by a simpler technology - heat.

Researchers reveal a new metabolic mechanism involved in resistance to lung cancer treatments A research team from the University of Valencia (UV) and the La Fe Health Research Institute (IIS La Fe) has identified a mechanism that explains why certain lung tumours with mutations in the EGFR gene stop responding to the most commonly used targeted therapies.

Scientists from the University of Galway in Ireland and the Institute of Oncology Research (IOR, affiliated to USI and member of Bios+) in Bellinzona have uncovered a new natural compound from Irish marine life that shows promise against a difficult-to-treat form of blood cancer. The team studied over 400 extracts from marine samples collected along the Irish coast.

Hilhorst focuses on the cardiovascular domain, specifically on blood vessels. What if new medical treatments could be tested entirely on a computer-without involving a single human or animal? With his PhD research, Pjotr Hilhorst is taking the first step in that direction. The TU/e researcher develops computer models and uses data from "virtual patients" to improve medical diagnostics and predict the effectiveness of procedures and medications.

Before a new treatment can save a life, it must be tested. Yet across Canada, more trials need to be conducted. Researchers at Schulich School of Medicine & Dentistry are collaborating with local partners to strengthen London, Ont. as a leading centre in clinical trials, aiming to improve care through evidence and collaboration.

Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are switched on. Using a new technique called MCC ultra, the team mapped the human genome down to a single base pair, unlocking how genes are controlled, or, how the body decides which genes to turn on or off at the right time, in the right cells.

A recently unearthed ancient monument in southeastern Mexico was built as a giant representation of the Mesoamerican universe, and was likely an important ceremonial site, finds new research by an international team involving a UCL archaeologist. The paper, published in Science Advances , describes the ancient complex of raised causeways, corridors carved into the earth and series of canals discovered at Aguada Fénix in 2020.

A University of Manchester study funded by Breast Cancer Now and supported by Prevent Breast Cancer, reveals a drug approved for use in other conditions could be repurposed to prevent breast cancer in women before the menopause. Researchers at the Manchester Breast Centre, based at The University of Manchester, found that blocking the effects of the hormone progesterone, using ulipristal acetate, a drug already used on the NHS, may reduce the risk of breast cancer developing in women before the menopause, with a strong family history of the disease.

As the body ages, brown adipose tissue activity decreases, fewer calories are burned, and this can contribute to obesity and certain chronic cardiovascular diseases that worsen with age. A study led by the University of Barcelona has identified a key molecular mechanism in the loss of brown fat activity during ageing.

Global agricultural practices exacerbate heat stress and pressure on water resources, warn VUB researchers With population growth and rising food demand, the area of land equipped for irrigation has increased almost six-fold worldwide since 1900. New research, published in three scientific papers led by the Vrije Universiteit Brussel (VUB) and ETH Zurich, shows that this rapid expansion of irrigation is having increasing effects on the health of populations, due to more intense wet heat stress and increased pressure on water resources.

Ageing stars may be destroying the giant planets orbiting closest to them, according to a new study by astronomers at UCL and the University of Warwick. Once stars like the Sun run out of hydrogen fuel, they cool down and expand to become red giants. In the Sun's case this will happen in about five billion years.

In order to understand brain diseases, neuroscientists try to untangle the intricate nerve fibre labyrinth of our brain. Before analysing brain tissue under a microscope, it is often soaked in paraffin wax to achieve high-quality sections. However, accurately mapping the densely packed nerves inside wax-treated brain slices was so far not possible.

Upwelling of phosphorus-rich deep water promotes an N-fixing symbiont of the Sargassum algae giving it a competitive advantage. Each year, vast mats of Sargassum spread across the tropical Atlantic, fouling Caribbean coastlines. Analyses of coral drill cores help explain the mechanism that drives these brown algal blooms.

Cambridge researchers have discovered why living in a disadvantaged neighbourhood may be linked to an increase in an individual's risk of dementia. Where you live clearly plays an important role in your brain health and risk of dementia, putting people living in deprived neighbourhoods at a serious disadvantage John O'Brien In research published today, they show how it is associated with damage to brain vessels - which can affect cognition - and with poorer management of lifestyle factors known to increase the chances of developing dementia.

Cambridge researchers have discovered why living in a disadvantaged neighbourhood may be linked to an increase in an individual's risk of dementia. Where you live clearly plays an important role in your brain health and risk of dementia, putting people living in deprived neighbourhoods at a serious disadvantage John O'Brien In research published today, they show how it is associated with damage to brain vessels - which can affect cognition - and with poorer management of lifestyle factors known to increase the chances of developing dementia.

Children faced a substantially higher risk of rare heart complications from being infected with COVID-19 during the pandemic than from being vaccinated against the disease, finds a new UCL-led study which compared the two scenarios for the first time. The study, published in The Lancet Child and Adolescent Health , looked at the electronic health records of nearly 14 million children in England under the age of 18 between 1 January 2020 and 31 December 2022.

Hidden genetic variations: biologist Joachim Kurtz talks about a special mechanism of evolution Since the discoveries made by the British naturalist Charles Darwin, one thing is clear: inherited differences between individuals are a decisive condition for evolutionary adaptation in organisms. Via the formation of proteins, they lead to different characteristics.